Does plant medicine work for anxiety?

Anxiety is a persistent problem that is estimated to impact more than 15% of the population.

A common problem with anxiety is that nerves are overstimulated.

Our nervous system has a natural response to calm the nerves using a non-standard amino acid called GABA or gamma-aminobytyric acid.

Our central nervous system and brain has GABA receptors that when bound with GABA will provide a calming response.

Gamma‐aminobutyric acid (GABA) is a nonstandard amino acid that acts as the principal inhibitory neurotransmitter in central nervous system (CNS) function.

What is a popular prescription drug for GABA receptors?

One of the most common ones is known as benzodiazepines including lorazepam, alprazolam, diazepam.

Is there any research evidence that plant medicine or phytomedicine can help relieve anxiety?

 

A recent study published in the journal phytotherapy research suggests the answer is “yes”.

Kava

Valerian

Pennywort

Hops

Here are more clinical trials that have looked at plant medicine for improving mood

Chamomile

Ginkgo biloba

Passionflower

Ashwagandha

Skullcap

Lemon balm.

 

Here is what the authors had to say

Of the phytomedicines reviewed, P. methysticum has the largest evidence base for use in the anxiety disorders, with tripartite level of support from in vitro, in vivo, and human clinical studies.

And

The number of positive findings from human studies of P. methysticum within randomised, well‐controlled trials also supports its use as a treatment for various anxiety disorders and associated symptoms, demonstrating broad clinical utility

And

V. officinalis, C. asiatica, M. recutita, G. biloba, P. incarnata, and W. somnifera offer the next most extensive evidence for reducing anxiety through GABA‐related pathways

 

Reference

GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Phytotherapy Research. 2018; Volume 32 (Issue 1): pages 3-18.

Jeremy Johnson, PharmD, PhD


Categories: Mental Health, Mood, Plant Medicine