If you are a coffee drinker you may want to read what impact the results of a new study with coffee found.
With coffee being one of the most consumed beverages in the world caffeine could be an important contributor to promoting overall health.
Caffeine is a xanthine alkaloid that has many different roles on biological processes.
For example, caffeine is known to increase metabolic rates, increase energy expenditures, have thermogenic activity, have lipolytic activity (i.e. fat break down) and make have antioxidant activity.
There are other compounds in coffee that include chlorogenic acids, trigonelline, melanoidins, and cafestol and kawhweol which have also have health promoting properties. 
More specifically, chlorogenic acids have been shown to increase the activity of genes involved in regulating energy intake and body fat.
This study published in Molecular Nutrition and Food Research evaluated the effect of coffee on inflammatory processes.
To do this they evaluated the white blood cells known as peripheral blood mononuclear cells (PBMCs) that were stimulated with chemicals that cause inflammation.
Here are the study details:
Healthy patients who had blood drawn with and without consuming coffee.
White blood cells (PBMCs) were isolated and stimulated with lipopolysaccharide (LPS) which is implicated in inflammation.
Here are the main results:
– A significant change in inflammation mediators IL6, IL8, GROA, CXCL2, CXCL5 as well as PGA2, PGD2, prostaglandin E2 (PGE2), LTC4, LTE4, and 15S-HETE was observed.
– Interestingly, some patients experienced a decrease in inflammatory markers while some experienced an increase in markers of inflammation
Take away message: The results suggest that simply consuming coffee is not a predictor for determining if inflammation will be decreased. There is clearly a relationship between coffee exerting an effect on inflammation, however, what was most surprising was patients either experienced an increase OR a decrease in inflammation. These results suggest a clear biological role of coffee, however, there must be underlying variables that are contributing to these results. Further research is clearly needed to determine in what types of patients coffee may be benefitical for reducing markers of inflammation.
His research on plant medicine has led to more than 45 publications and abstracts.This research has been presented at international meetings in the USA, France, Turkey, Peru, Israel, Austria, and Italy.
Categories: Antioxidant, Inflammation, Plant Medicine
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